University of California, San Francisco
Stimulus

Challenge Grants in Health and Science Research (RFA-0D-09-003)

Purpose. The NIH invites Challenge Grant (RC1) applications from domestic (United States) institutions/organizations proposing novel research in areas that address specific knowledge gaps, scientific opportunities, new technologies, data generation or research methods that would benefit from an influx of funds to quickly advance the area in significant ways. This program is designed to support research in scientific areas identified by the institutes and centers, as identified in the specific challenge areas and topics. Click on the Challenge Area for the detailed description of the specific Challenge Topics within that area that have been accorded the highest priority by the NIH institute, center or office indicated.

(01) Behavior, Behavioral Change, and Prevention
(02) Bioethics
(03) Biomarker Discovery and Validation
(04) Clinical Research
(05) Comparative Effectiveness Research (CER)
(06) Enabling Technologies
(07) Enhancing Clinical Trials
(08) Genomics
(09) Health Disparities
(10) Information Technology for Processing Health Care Data
(11) Regenerative Medicine
(12) Science, Technology, Engineering and Mathematics Education (STEM)
(13) Smart Biomaterials – Theranostics
(14) Stem Cells
(15) Translational Science

Institutes and centers have identified additional Challenge Topics for funding under this FOA. A compilation of all Challenge Topics can be accessed in a single omnibus.

Individual institutes and centers have also listed their particular topics on their own websites.

Note: The broad Challenge Area and the specific Challenge Topic being addressed must be explicitly cited in the Project Summary/Abstract Component of the application.

Note: Approximately 200 high-priority Challenge Topics have been identified, and more than 900 are listed in the omnibus.

•    Application Submission/Receipt Date. April 27, 2009.
•    Funds Available and Anticipated Number of Awards. NIH has designated at least $200 million in FYs 2009-2010 to fund 200 or more grants, contingent upon the submission of a sufficient number of scientifically meritorious applications. In addition, funds allocated to NIH specifically for comparative effectiveness research (CER) may be available to support additional grants.
•    Budget and Project Period. Budget requests should be commensurate with project needs up to a two-year project period. The requested budget may not exceed $500,000 total costs per year for a maximum of $1 million total costs over a two-year project period. Total cost is defined as the sum of direct and indirect costs. Cost sharing is not required. Funding requested for any foreign component should not exceed 10% of the total requested direct costs or $25,000 (aggregate total for all subcontracts and subawards), whichever is less.
•    Page Limits: The Research Plan is limited to 12 pages.
•    Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge and resources necessary to carry out the proposed research are invited to work with their institution or organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
•    Early Stage Investigators (ESIs)/New Investigators (New PIs). New PIs and Early Stage Investigators (ESIs) are invited to apply for Recovery Act Challenge Grants in Health and Science Research. Because the awards made under this program are substantial competing NIH research grants, recipients will not be considered New PIs or ESIs when they apply for NIH research grants in the future. More information can be found here.
•    Number of PDs/PIs. More than one PD/PI (i.e., multiple PDs/PIs) may be designated on the application.
•    Number of Applications. Applicants may submit more than one application, provided each application is scientifically distinct.
•    Resubmissions. Because this is a one-time-only solicitation, resubmissions are not permitted.
•    Renewals. Renewals are not permitted in response to this FOA.
•    Review Criteria. Enhanced Review Criteria will be used.

Please click here for the full program announcement.